For an isometry $A$ on Hilbert space $H$, the task of an efficient orthogonalization of the Krylov sequence $x$, $Ax$, $A^2x$, $\ldots$ (with additional specific subtractions admitted) is addressed and solved in a matrix generalization where $x \to M_j$ becomes a sequence of $p-$plets of elements of $H$. Several samples of applicability (like the study of structured Toeplitz matrices, of the role of circulants or of a reduction of $A$ to a product of plane rotations etc) are mentioned. Connections with the Gram-Schmidt approach, $QR$ factorization technique and generalized Schur algorithm (with displacements) are discussed and a few encouraging numerical comparisons are added. MR2312401 Stewart, Michael A generalized iosmetric Arnoldi algorithm. Linear Algebra Appl. 423 (2007), no. 2-3, 183--208. 65F15